2004-10-20 21:24:02暈炫
NEJM.Tx for proliferative lupus nephritis
NEJM, 2004, March, original
After induction by Pulse therapy with Cyclophosphamide
Inclusive criteria
1. Lupus nephritis, WHO class III or IV
maintain Tx: Imuran & Cellcept were better than Endoxon
Immuran VS Endoxon
1. patient survival
2. Event free survival(chronic renal failuer)
3. Less Total, Major infection,
4. Less Nausea, vomiting
Cellcept VS Endoxon
1. Relapse free survival
2. Less Total, Major infection
3. Less Nausea, vomiting
After induction by Pulse therapy with Cyclophosphamide
Inclusive criteria
1. Lupus nephritis, WHO class III or IV
maintain Tx: Imuran & Cellcept were better than Endoxon
Immuran VS Endoxon
1. patient survival
2. Event free survival(chronic renal failuer)
3. Less Total, Major infection,
4. Less Nausea, vomiting
Cellcept VS Endoxon
1. Relapse free survival
2. Less Total, Major infection
3. Less Nausea, vomiting